DESIGN, SYNTHESIS, AND INVESTIGATION OF NOVEL NITRIC OXIDE (NO)-RELEASING AROMATIC ALDEHYDES AS DRUG CANDIDATES FOR THE TREATMENT OF SICKLE CELL DISEASE

Sickle cell disease (SCD) is caused by a single-point mutation, and the ensuing deoxygenation-induced polymerization of sickle Tapestry hemoglobin (HbS), and reduction in bioavailability of vascular nitric oxide (NO), contribute to the pathogenesis of the disease.In a proof-of-concept study, we successfully incorporated nitrate ester groups onto tw

The approach of World Toy Storage Trade Organisation towards energy has been subject of many debates.One of the important issues is whether member States are obliged to free the energy transportation via pipeline or not.Logically, the mentioned freedom is conceivable in two forms, i.e.third party access and capacity establishment.Amongst the main d

This article examines gender and cultural sense-making in relation to perfumes and their packaging.Gendered meanings of seduction, choice, consumption and taste Course a pied - Homme - Vetements - Short - 3-4" are brought to the fore with the use of go-along interviews with consumers in per-fume stores.Meeting luxury packages in this feminized envi